Mental Health

Major Depressive Disorder

MDD is a medical condition that affects mood, energy, thinking, and daily function. Early treatment leads to better outcomes.

Symptoms

Persistent low mood, loss of interest, fatigue, appetite changes, sleep disruption, difficulty concentrating, and feelings of worthlessness.

Causes and risk

Genetics, brain chemistry, trauma, chronic stress, medical illness, and substance use.

How it is evaluated

Thorough symptom review, safety assessment, screening for co-occurring conditions, and discussion of treatment goals.

Treatment

Psychotherapy, antidepressant medication, lifestyle changes, and in severe cases referral for advanced interventions.

Questions

Depression is persistent (at least two weeks) and impairs functioning. Sadness typically passes.

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